Neurofibromatosis Early Stages Pictures - 13 Photos & Images
Neurofibromatosis usually appears in childhood. Signs are often evident at birth or shortly afterward, and almost always by age 10. Signs and symptoms are often mild to moderate, but can vary in severity.
Signs and symptoms include:
- Flat, light brown spots on the skin (cafe au lait spots). These harmless spots are common in many people. Having more than six cafe au lait spots is a strong indication of NF1. They are usually present at birth or appear during the first years of life and then stabilize.
- Freckling in the armpits or groin area. Freckling usually appears by ages 3 to 5. Freckles are smaller than cafe au lait spots and tend to occur in clusters in skin folds.
- Tiny bumps on the iris of your eye (Lisch nodules). These harmless nodules can't easily be seen and don't affect your vision.
- Soft bumps on or under the skin (neurofibromas). These benign tumors usually develop in or under the skin, but can also grow inside of the body. Sometimes, a growth will involve multiple nerves (plexiform neurofibroma).
- Bone deformities. Abnormal bone growth and a deficiency in bone mineral density can cause bone deformities such as a curved spine (scoliosis) or bowed lower leg.
- Tumor on the optic nerve (optic glioma). These tumors usually appear by age 3, rarely in late childhood and adolescence, and almost never in adults.
- Learning disabilities. Impaired thinking skills are common in children with NF1, but are usually mild. Often there is a specific learning disability, such as problem with reading or mathematics. Attention-deficit/hyperactivity disorder (ADHD) is also common.
- Larger than average head size. Children with NF1 tend to have a larger than average head size due to increased brain volume.
- Short stature. Children with NF1 often are below average in height.