Pemphigus Vegetans Pictures - 34 Photos & Images
Pemphigus vulgaris is an autoimmune disorder characterized by production of IgG autoantibodies against intercellular adhesion protein desmoglein, leading to acantholysis. Pemphigus vegetans is a rare variant of pemphigus vulgaris characterized by heaped up, cauliflower-like vegetating plaques in the flexures. The disorder affects chiefly middle-aged adults. Lesions are primarily flexural, although vegetations may occur at any site. We report a case of pemphigus vegetans involving the oral mucosa and perioral region which was initially mistaken for malignancy due to its unusual presentation.